|
KMID : 1123920030170020476
|
|
Korean Journal of Oriental Physiology and Pathology
2003 Volume.17 No. 2 p.476 ~ p.480
|
|
|
Screening of Cytotoxicity and Antimicrobial Effects of Hexane Extracts from Cornis fructus
|
|
Chun Hyun-Ja
Choi Won-Hyung
Lee Jeong-Ho
Yang Hyun-Ok
Baek Seung-Hwa
|
|
|
Abstract
|
|
|
|
Cornis fructus was extracted by successive extraction and then fractionated with hexane extract to get active fractions. This study was performed to determine the cytotoxic effect of hexane extract from Cornis fructus on NIH 3T3 fibroblasts and cancer cell lines using MTT assay. Hexane extract showed cytotoxic effect against A549, B16 melanoma and MDA-MB-231. Futher fractionation with hexane extract was performed to obtain effective fraction, fraction 3 showed the cytotoxic effect against A549 and MDA-MB-231. In antimicrobial test of each fraction of hexane extract, fraction 5 showed antimicrobial activities against P. putida and P. aeruginosa.
|
|
|
KEYWORD
|
|
|
Corni fructus, MTT assay, Cytotoxic effects, Antimicrobial activities
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|